TAAV-manufactured enzymatic neDNA™ is a critical starting material that provides comparable productivity and potency to plasmid-derived recombinant Adeno-Associated Vectors (rAAV) vectors and increases efficiency compared to plasmid, as less input DNA is required in transfections.

This study highlights the advantages of using neDNA™, a critical starting material with high-quality and minimal contaminants, that may resolve the challenges in rAAV production, since enzymatic DNA amplification offers rapid production, scalability, and robustness.